We are a computational genomics lab studying the etiology of developmental disorders and complex human diseases using high-dimensional genomic data. Our lab utilises a range of genomics and systems biology approaches to better understand regulatory features and cellular trajectory underlying disease development.
We focus on:
The An Lab is a computational biology research group specializing in advanced genomic analysis and AI-driven modeling. Our work focuses on long-read whole-genome sequencing, multi-omics integration, and cloud computing for large-scale data processing. We are also developing LLM-based deep learning models to enhance genomic data interpretation and analysis.
We work with closely with international collaborators, including the Sanders Lab at Oxford and the Werling lab at University of Wisconsin-Madison. Our team is a part of the Korean autism WGS consortium and closely collaborates with Prof. Hee Jeong Yoo at Seoul National University Bundang Hospital.
If you are interested in joining please go to the join us page.
We are grateful for funding from the National Research Foundation of Korea.
We wrote a review on national biobank projects utilizing whole-genome sequencing for population-scale genomics (link)
Feb 18th 2025Excited to share our latest paper on aberrant ERK signaling in astrocytes and its impact on learning and memory in RASopathy-associated BRAF mutant mouse models! (link)
Feb 7th 2025Congrats! Hyeji and Chanhee got the Best Posters Awards for the 33th International KOGO Annual Conference!🎉
Jan 6th 2025Our latest study explores potential causal genes for undiagnosed congenital anomalies using a trio-based whole-genome sequencing (link)
Dec 6th 2024Congrat Yujin for the Outstanding Presentation Award at 2024 International Joint Conference of KSMGG & EAUHGS!🎉
Nov 25th 2024Find our latest paper on m6A-binding proteins YTHDFs suppress IFN-γ signaling, attenuating cancer immunity and ICI responsiveness in gastic cancer (link).
Nov 24th 2024Excited to share our latest paper on multiomics subtyping for non-small cell lung cancer (link).
Oct 30th 2024Seunghwan and I wrote a review for multiomics in cancer biomarker discovery and cancer subtyping (link).
Oct 26th 2024Congrat Yujin and Seoyeon for the best paper awards at BIOINFO 2024! Also congrats Ingyeong for the excellent poster awards and Yebin for the best poster awards! 🎉