Welcome to An Lab at Korea University

We are a computational genomics lab studying the etiology of developmental disorders and complex human diseases using high-dimensional genomic data. Our lab utilises a range of genomics and systems biology approaches to better understand regulatory features and cellular trajectory underlying disease development.

We focus on:

• Understanding the genetic architecture of autism.
• Leveraging whole genome sequencing (WGS) and single cell analyses to understand neurodevelopment and disorders.
• Integrating multiomics data to better understand genetic heterogeneity in human disorders.

Technologies and methods

The An Lab is a computational biology research group specializing in advanced genomic analysis and AI-driven modeling. Our work focuses on long-read whole-genome sequencing, multi-omics integration, and cloud computing for large-scale data processing. We are also developing LLM-based deep learning models to enhance genomic data interpretation and analysis.

Collaborators

Korean Autism Research Consortium (KARC)

Our team is a part of the Korean autism research consortium (KARC) and closely collaborates with Prof. Hee Jeong Yoo at Seoul National University Bundang Hospital.

International Collaborations

We work closely with international collaborators, including:

• Stephan Sanders at Oxford
• Donna Werling at University of Wisconsin-Madison
• Stephen Scherer and Brett Trost at SickKids Hospital
• Anders D. Børglum and Jakob Grove at iPSYCH, Aarhus, Denmark

Joining An Lab

If you are interested in joining please go to the join us page.

Funding

We are grateful for funding from the National Research Foundation of Korea.