Welcome to An Lab at Korea University

We are a computational genomics lab studying the etiology of developmental disorders and complex human diseases using high-dimensional genomic data. Our lab utilises a range of genomics and systems biology approaches to better understand regulatory features and cellular trajectory underlying disease development.

We focus on:

• Understanding the genetic architecture of autism.
• Leveraging whole genome sequencing (WGS) and single cell analyses to understand neurodevelopment and disorders.
• Integrating multiomics data to better understand genetic heterogeneity in human disorders.

Technologies and methods

The An Lab is primarily a computational biology group that uses a wide range of genomic, bioinformatic, and statistical methods including: whole-genome sequencing, single cell RNA/ATAC-seq, multi-omics, and cloud computing.

Collaborators

We work with closely with international collaborators, including the Sanders Lab at Oxford, the Werling lab at University of Wisconsin-Madison, and the Minah Kim Lab at Columbia University. Our team is a part of the Korean autism WGS consortium and closely collaborates with Prof. Hee Jeong Yoo at Seoul National University Bundang Hospital.

Joining An Lab

If you are interested in joining please go to the join us page.

Funding

We are grateful for funding from the National Research Foundation of Korea and Korea Dementia Research Center.