Eunhyong’s research interests are focused on unraveling the biological mechanisms that underlie cancer biology, with a particular emphasis on the analysis of multi-omics data. Given the prevalence of chromosomal aneuploidy across all types of cancer, her research efforts are centered on deciphering the cancer subtypes that exhibit whole genome doubling (WGD) features, as well as elucidating the kinase network of these subtypes. Through her research, Eunhyong aims to provide a comprehensive understanding of the heterogeneous mutational and biological processes that lead to WGD in human cancer.
By studying the kinases that are associated with cancer subtypes exhibiting WGD features, Eunhyong hopes to identify novel therapeutic targets that could be used to develop more effective treatments for cancer. Her research may also shed light on the fundamental mechanisms that drive the development and progression of cancer, paving the way for new approaches to cancer prevention and management. Her research aims to contribute to the growing body of knowledge on the genetic and molecular underpinnings of cancer, with potential implications for the development of more effective diagnostic and treatment strategies.
Education & Training
- 2022-2024 M.Sc., Student, Department of Integrated Biomedical and Life Science, Korea University
- 2018-2022 B.Sc., Biosystem and Biomedical Sciences, Korea University
Publication
- Song KJ✻, Choi S✻, Kim K✻, Hwang HS✻, Chang E, Park JS, Shim SB, Choi S, Heo YJ, An WJ, Yang DY, Cho KC, Ji W, Choi CM, Lee JC, Kim HR, Yoo J, Ahn HS, Lee GH, Hwa C, Kim S, Kim KG, Kim MS, Paek E, Na S†, Jang SJ†, An JY†, Kim KP†, Proteogenomic Analysis of a Korean Cohort Reveals Lung Cancer Subtypes Predictive of Metastasis, Chromosome Instability, and Tumor Microenvironment, Nature Communications, 2024
- Chang E✻, Kim SJ, Hwang HS, Song KJ, Kim K, Kim MS, Jang SJ, You S, Kim KP†, An JY†, Pan-cancer proteogenomic landscape of whole-genome doubling reveals putative therapeutic targets in various cancer types, Clinical and Translational Medicine, 2024
- Chang E✻ & An JY†, Whole-genome doubling is a double-edged sword: the heterogeneous role of whole-genome doubling in various cancer types, BMB Reports, 2024
Awards
- 2024 Young scientist award, 22th Annual International Proteomics Conference, Korean Human Proteome Organization
- 2024 Excellent poster award, 22th Annual International Proteomics Conference, Korean Human Proteome Organization
- 2023 Excellent poster award, Annual Conference of Korean Society for Bioinformatics
- 2023 Graduate Fellowship, Kwanjeong Educational Foundation (2023-2024)
- 2022 Excellent poster award, Annual Conference of Korean Society for Bioinformatics