Seoyeon is interested in leveraging sequencing data and bioinformatics to understand the molecular basis of human genomics. To this end, she actively collaborates with proteomics, transcriptomics, and epigenomics experts, employing her own statistical and computational techniques.

During her training, Seoyeon initiated the analysis of transcriptomics data to elucidate the fundamental interactions of inflammatory bone marrow cells. She led collaboration with various experts and solidified her framework in interpreting immune biology using sequencing data. Expanding beyond immunology, she has applied her insights to decipher the impact of valproic acid on the manifestation of fetal ASD, as demonstrated in her work (Park et al., 2023).

Seoyeon is actively engaged in collaborations across diverse fields of single-cell data, with a specific emphasis on the immune and nervous systems. Her current research explores dynamic changes in transcriptomic and epigenomic profiles during neurodevelopment through large-scale integration of single-cell data.

Education & Training

• 2022-2024 M.Sc., Department of Integrated Biomedical and Life Science, Korea University
• 2018-2022 B.Sc., Biosystem and Biomedical Sciences, Korea University

Publication

• Kim S✻, Lee J✻, Koh IG, Ji J, Kim HJ, Kim E, Park J, Park JE, An JY†, An integrative single-cell atlas to explore the cellular and temporal specificity of neurological disorder genes during human brain development, Experimental & Molecular Medicine, 2024
• Song KJ✻, Choi S✻, Kim K✻, Hwang HS✻, Chang E, Park JS, Shim SB, Choi S, Heo YJ, An WJ, Yang DY, Cho KC, Ji W, Choi CM, Lee JC, Kim HR, Yoo J, Ahn HS, Lee GH, Hwa C, Kim S, Kim KG, Kim MS, Paek E, Na S†, Jang SJ†, An JY†, Kim KP†, Proteogenomic Analysis of a Korean Cohort Reveals Lung Cancer Subtypes Predictive of Metastasis, Chromosome Instability, and Tumor Microenvironment, Nature Communications, 2024
• Park G✻, Jang WE✻, Kim S✻, Gonzales EL, Ji J, Choi S, Kim YJ, Park JH, Mohammad HB, Bang G, Kang M, Kim SB, Jeon SJ, Kim JY, Kim KP, Shin CY†, An JY†, Kim MS†, Lee YS†, Dysregulation of the Wnt/β-catenin signaling pathway via Rnf146 upregulation in a VPA-induced mouse model of autism spectrum disorder, Experimental and Molecular Medicine, 2023
• Park HR✻, Shiva A, Cummings P, Kim S, Kim S, Lee E, Leong A, Chowdhury S, Shawber C, Carvajal R, Thurston G, AN JY, Lund AW, Yang HW, Kim M†. Angiopoietin-2-dependent spatial vascular destabilization promotes T-cell exclusion and limits immunotherapy in melanoma, Cancer Research, 2023.

Awards

• 2024 Best paper award, Annual Conference of Korean Society for Bioinformatics
• 2023 Research Poster Award, BK21 L-HOPE graduate symposium
• 2023 AOHUPO Best Posters Award, HUPO World Congress
• 2022 Outstanding Poster Award, Annual Conference of Korean Society for Bioinformatics
• 2022 Outstanding Poster Award, International Conference: Korean Society for Molecular and Cellular Biology